Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps1-09-04 | Thyroid Cancer | ETA2023

Development and pre-clinical validation of next-generation sequencing gene panel to detect clinically relevant mutations in thyroid cytological and histological samples

Nacchio Mariantonia , Ingenito Maria , Salatiello Maria , Vigliar Elena , Malapelle Umberto , Troncone Giancarlo , Bellevicine Claudio

Objectives: Molecular techniques are becoming increasingly important for the management of thyroid nodules. In particular, next-generation sequencing (NGS) can assess multiple predictive biomarkers simultaneously, enabling more accurate pre-operative risk stratification for patients with indeterminate fine-needle aspirates and identifying specific molecular alterations for targeted therapy in patients affected by advanced, radioactive iodine refractory carcinomas. To meet thes...